A decrease in the level of SOD and GPx was observed in simvastatin-treated and hypercholesterolemic control groups. (a) Evaluation…, Evaluation of weight loss in response to leaf and seed extract in Swiss…, Comparison of cell growth inhibition of leaf and seed extract of B. alba…, Fluorescence and optical microscopic observation…, Fluorescence and optical microscopic observation of EAC cells for control mice and treated…, Agarose gel electrophoresis of extracted…, Agarose gel electrophoresis of extracted DNA, RNA, and PCR product from EAC cells…, Gene expression level analysis of treated mice's mRNA with control based on their…, NLM In this study, 25 medicinal plant methanol extracts were screened for anti-HMG-CoA reductase activity. Blood samples were collected at 0, 4, 8, and 12th week via ear marginal vein using 23-gauge butterfly needle and 3 mL syringes into EDTA and heparinised tubes. Basella cordifolia Lam. This study was designed to investigate the hypocholesterolemic and antiatherosclerotic effects of Basella alba ( B. alba ) using … Basella alba is a herbaceous, perennial vine cultivated as a leafy vegetable and ornamental in tropical and subtropical and occasionally extending into temperate regions as an annual. After filtration, the residue obtained was again resuspended in equal volume of 95% ethanol for 48h and filtered again. COVID-19 is an emerging, rapidly evolving situation. Basella alba, la baselle ou épinard de Malabar, est une espèce de plantes dicotylédones de la famille des Basellaceae, probablement originaire d'Asie du Sud. 2016 Jul 12;16:211. doi: 10.1186/s12906-016-1185-y. rubra) become synonymous to B. alba as treated in Fl.China, GRIN etc. It contains a high amount of oxalate, that can bind with calcium and iron and cause your body to absorb less of these important nutrients. -. Due to their adverse side effects, it is challenging to develop new drug for cancer treatment. Changes on body weight of rabbits between different groups. Toxicol Res. USA.gov. A. Adaramoye, V. O. Nwaneri, K. C. Anyanwo, E. O. Farombi, and G. O. Emerole, “Possible anti-atherogenic effect of kolaviron (a, J.-R. Nofer, B. Kehrel, M. Fobker, B. Levkau, G. Assmann, and A. V. Eckardstein, “HDL and arteriosclerosis: beyond reverse cholesterol transport,”, G. Assmann and A. M. Gotto Jr., “HDL cholesterol and protective factors in atherosclerosis,”, O. A significant cytotoxic activity was also found in both leaf and seed extract. 2010;9:6952–6955. 1 1 Nutrient management and effects of netting on growth and yield 2 of Indian spinach (Basella alba) 3 M. Mishu Akther1, M. Ashraful Islam 1*, M. Saidee Rahman1, M. Rezaul Karim 1, 4 Dilip Nandwani2 5 1Department of Horticulture, Bangladesh Agricultural University, Mymensingh 2202, 6 Bangladesh; firstname.lastname@example.org (M.M.A); email@example.com (M.A.I. Basella Alba is a herb used commonly alongside Hibiscus macranthus for the purpose of fertility. Journal of Ethnopharmacology, 65, 1999. and it involves a complex array of enzyme activation, migration, tissue breakdown and repair -3354 on: 17 -03 2012 Revised on: 17-04-2012 Accepted on: 23-04-2012 DOI: 10.7324/JAPS.2012.2413 granuloma method. Free radicals, oxidative stress, and antioxidants in human health and disease. Basella alba (B. alba) extract showed the highest enzyme inhibition, about 74% . Basella alba commonly known as Indian Spinach belonging to family Basellaceae is a fast growing perennial vine native to tropical Asia, probably originating from India or Indonesia and extremely heat tolerant. ), AST (37.3 and 43.7%, resp. One-way analysis of variance (ANOVA) followed by Dunnett’s post hoc test for multiple comparisons among the groups was performed. In: Bajaj Y. P. S (ed). The current treatment options of cancer are radiotherapy, chemotherapy, hormone therapy, and surgery, where all of them have unpleasant side effects. 9399800. Effects of aqueous extract of Basella alba leaves on haematological and biochemical parameters in albino rats. In previous study, we have screened the HMG CoA reductase inhibitory activity of 25 medicinal plants extracts. The marker enzymes, ALT and AST, were evaluated to detect the liver damage while CK was used to diagnose the muscle injury. It is well known that the hypocholesterolemic drugs are effective in lowering LDL but the long term consumption causes adverse effects such as liver and muscle injuries, rhabdomyolysis, myopathy, and acute renal failure. Fluorescence and optical microscopic observation of EAC cells for control mice and treated mice. The rabbits were randomly divided into 5 groups (): Group 1: control rabbits fed with standard diet for 12 weeks; Group 2: rabbits fed with 2% high cholesterol diet (HCD) for 12 weeks; Group 3: rabbits fed with 2% HCD for 8 weeks and treatment with simvastatin (10 mg/kg) for 4 weeks; Group 4: rabbits fed with 2% HCD for 8 weeks and treatment with B. alba extract (100 mg/kg) for 4 weeks; and Group 5: rabbits fed with 2% HCD for 8 weeks and treatment with B. alba extract (200 mg/kg) for 4 weeks. | Leaves are fleshy, ovate or heart-shaped, 5 to 12 cms long, stalked, tapering to a pointed tip with a cordate base. In contrast, a significant decrease noted in serum HDL in hypercholesterolemic rabbits was also reported by Ismail et al. 1992. It is listed as a potential environmental weed in Australia and as a weed of sugarcane fields on Iriomote Island, Japan. Another similar situation can be seen in Vitex negundo var. An ethnomedicine survey in southern India revealed that Basella alba is one of the plants used for the treatment of apthae. No need to register, buy now! Copyright © 2015 Gunasekaran Baskaran et al. Characterization and evaluation of antibacterial and antiproliferative activities of crude protein extracts isolated from the seed of Ricinus communis in Bangladesh. B. alba at dose of 200 mg/kg has significantly higher hypocholesterolemic effect than that of 100 mg/kg. Representative photographs of rabbits’ aortic arch from 5 groups stained with H&E. The traditional medicinal plant Basella alba belongs to Basellaceae. A Pharm Biol. Hypercholesterolemia is the major risk factor that leads to atherosclerosis. In our present study, feeding hypercholesterolemic diet for 8 weeks leads to the reduction in the activities of SOD and GPx. Treatment with both … The crude methanolic extract of B. alba was concentrated using rotary evaporator (Heidolph) under reduced pressure at 40°C and freeze-dried at −40°C for further analysis. Hypercholesterolemia is the major risk factor that leads to atherosclerosis. Stems are purplish or green. About equal level of expression was found in GAPDH mRNA and upregulation of p53 and downregulation of antiapoptotic Bcl-2 were found in the treated cells compared to control. Effects of B. alba on fasting blood glucose in stressed rats The FBG of group 4 (85.2 ± 1.49 mg/dL) and group 5 (72.8 ± 1.36 mg/dL) rats given 60 mg/kg of B. alba extract at the end of the second week were significantly higher than normal control (54.4 ± 1.86 mg/dL) but significantly lower than stress control (groups 2) (106.2 ± 4.55 mg/dL) and group 3 (114.86 ± 6.12 mg/dL). B. alba (200 mg/kg) increases the HDL level more effectively than simvastatin. Administration of B. alba at 100 and 200 mg/kg decreased TC level by 49 and 54.2%, respectively, LDL level by 45 and 50.1%, respectively, and TG level by 34.9 and 39.7%, respectively. It is also mostly found in the wild for example forests,swampy areas etc. Unless you are specifically allergic to Basella Alba, you should not experience side effects when eating this plant or consuming it in dietary supplements. Leaf extracts showed…, Cytotoxic activity of leaf and seed extract of B. alba . In Table 1, rabbits fed with 2% cholesterol diet for 12 weeks showed significant increase () in body weight compared to the normal control. Malabar spinach, Basella alba, is a popular green leafy vegetable in other parts of the world. Caution : Consult a Doctor before consuming it. As shown in Table 2, serum levels of TC, LDL, and TG were significantly higher () in rabbits fed with HCD compared to the normal diet group after 8 weeks. Basella alba is an important edible vegetable in India. Side Effects. | Twenty New Zealand white rabbits were divided into 5 groups and fed with varying diets: normal diet, 2% high cholesterol diet (HCD), 2% HCD + 10 mg/kg simvastatin, 2% HCD + 100 mg/kg B. alba extract, and 2% HCD + 200 mg/kg B. alba extract, respectively. Effects of the Methanol Extract of Basella alba L (Basellaceae) on Steroid Production in Leydig Cells Edouard Akono Nantia 1, Carine Travert 2, Faustin-Pascal T. Manfo 1, Serge Carreau 2, Thomas K. Monsees 3 and Paul Fewou Moundipa 1,* 1 Laboratory of Pharmacology and Toxicology, Department of Biochemistry, University of Yaoundé I, PO. chapter four 4.0 results and discussion. It is listed as a potential environmental weed in Australia and as a weed of sugarcane fields on Iriomote Island, Japan. Along with unique quality if nutrient, it … Symptoms include – itchy eyes, scratchy throat, nasal congestion, or hives. Ganapathy R., Sundara S., Mohan S., Kameshwaran. Accumulation of oxidized LDL leads to atherosclerotic plaque formation which contributes to stroke, myocardial infarction, and cardiovascular diseases (CVDs) . Publication Author Huxley. The lysate was then diluted with phosphate buffer (pH 7, 0.01 mol/L) and mixed thoroughly. Treatment with simvastatin and B. alba (100 and 200 mg/kg) for 4 weeks managed to reduce the body weight compared to the untreated hypercholesterolemic rabbits. Due to their adverse side effects, it is challenging to develop new drug for cancer treatment. Therefore, current study manifested that leaf and seed extracts of B. alba have antiproliferative activity against EAC cell line and can be a potent source of anticancer agents to treat cancer. B. alba leaves and a methanolic extract of the leaves inhibited the growth of S. litura larvae. This suggests high concentration of cholesterol and the usage of simvastatin caused liver and muscle damage [18, 19], whereas administration of B. alba extract for 4 weeks reduced the elevations of ALT, AST, and CK indicating its hepatic and muscle-protective effects. G1: normal control, G2: hypercholesterolemic control, G3: simvastatin-treated (10 mg/kg), G4: T. Yokozawa, E. J. Cho, S. Sasaki, A. Satoh, T. Okamoto, and Y. Sei, “The protective role of Chinese prescription Kangen-karyu extract on diet-induced hypercholesterolemia in rats,”, S. K. Yeap, B. K. Beh, W. Y. Ho et al., “In vivo antioxidant and hypolipidemic effects of fermented mung bean on hypercholesterolemic mice,”, S. Salvamani, B. Gunasekaran, N. A. Shaharuddin, S. A. Ahmad, and M. Y. Shukor, “Antiartherosclerotic effects of plant flavonoids,”, M. F. Ismail, M. Z. Gad, and M. A. Hamdy, “Study of the hypolipidemic properties of pectin, garlic and ginseng in hypercholesterolemic rabbits,”, G. Baskaran, S. Salvamani, S. A. Ahmad, N. A. Shaharuddin, P. D. Pattiram, and M. Y. Shukor, “HMG-CoA reductase inhibitory activity and phytocomponent investigation of, R. Adhikari, K. H. Naveen, and S. Shruthi, “A review on medicinal importance of, H. Yasmin, M. A. Kaisar, M. M. R. Sarker, M. S. Rahman, and M. A. Rashid, “Preliminary anti-bacterial activity of some indigenous plants of Bangladesh,”, P. Balachandran and R. Govindarajan, “Cancer—an ayurvedic perspective,”, A. The results revealed that the treatment with B. alba extract (100 and 200 mg/kg) significantly decreased () ALT (40.5 and 44.9%, resp. Basella alba leaf extract showed the highest inhibitory effect at about 74%. 2019 Nov 21;36(1):79-88. doi: 10.1007/s43188-019-00011-7. The aortic arch of the rabbits was removed, cleaned, dried, and fixed in 10% neutral buffer formalin. Like other natural herbs, Basella Alba has been used to treat low libido and infertility. Gas chromatography with tandem mass spectrometry … In general, B. alba treatment (200 mg/kg) showed no significant difference in intima/media ratio compared to simvastatin-treated group. Fruit is fleshy, stalkless, ovoid or spherical, 5-6 mm long, and … This study was designed to investigate the hypocholesterolemic and antiatherosclerotic effects of Basella alba (B. alba) using hypercholesterolemia-induced rabbits. A. One of the most reported adverse effects is an allergic reaction. Basella alba has been used for many of its useful product from ancient times. Side Effects of Malabar Spinach. Rahi MS, Islam MS, Jerin I, Jahangir CA, Hasan MM, Hoque KMF, Reza MA. Excess LDL is mostly deposited in arterial wall and becomes a main component of atherosclerotic plaque formation, while HCD feeding has been reported to reduce fatty acid oxidation, resulting in the increase of serum TG which is considered as another risk factor for CVDs . The atherosclerotic lesion was analyzed for the thickness of intima, media, and intima: media ratio of 4 rabbits per group under a light microscope equipped with image analyzer system (Olympus, Germany). levels while the treatment with simvastatin (10 mg/kg) showed significant elevation () in the levels of ALT (61.4%), AST (64.1%), and CK (34%). Basella Alba is an edible perennial vine, which grows leaves that look like spinach. Growth inhibition and apoptosis of Ehrlich ascites carcinoma cells by the methanol extract of Eucalyptus camaldulensis. The mechanism by which B. alba inhibits the atherosclerotic plaque is not known but may be due to its antioxidant, hypocholesterolemic, and antiatherosclerotic effects such as decreasing oxidative stress, lowering the LDL level, reducing inflammation, and inhibiting macrophage accumulation. In the present study, simvastatin, a potent hypocholesterolemic drug, was used as a positive control because it has known mechanism of action in inhibiting HMG-CoA reductase . International Journal of Phytopharmacology. Basella alba is a short-lived, perennial climbing plant, producing stems up to 9 metres long that scramble over the ground and twine into other plants for support[200. Cell growth inhibition was determined by haemocytometer whereas apoptosis of cancer cells were studied by florescence microscope using Hoechst-33342 stain and result was supported by DNA fragmentation and certain cancer related genes expression through PCR analysis. Asian Pacific Journal of Tropical Medicine. Nowadays, alternative treatment using medicinal plants gained much attention since the usage of statins leads to adverse health effects, especially liver and muscle toxicity. Health benefits of Nderema(basella alba) Basella also known as vine spinach is a popular tropical leafy green vegetable. There are few insects that cause damage to B. alba. Throughout the study, all the rabbits were kept in a 12 h light-dark cycle room with almost constant temperature at 23–25°C. Growth is slow in low temperatures resulting in low yields. B. alba leaf and seed extract exhibit a considerable scavenging activity in comparison to a standard antioxidant BHT. However, there are some side effects that people should be aware of when they are using Indian Spinach for medicinal purposes. 4.4 leaf area. Does Basella Alba Cause Side Effects? B. alba is a wild leafy vegetable, which is rare in its natural habitat, 11 but in recent times, it is an important leafy vegetable grown for its nutritive value 12 throughout the temperate regions as an annual and in the tropics as a … BMC Complement Altern Med. Basella crassifolia Salisb. Synthetic drugs, statins, are commonly used for the treatment of hypercholesterolemia. On the other hand, hypercholesterolemic control group (G2) caused alteration in the aortic wall with the appearance of a large atheromatous plaque and demonstrated a remarkable intimal thickening of aorta. The results from the present study showed that B. alba extract (200 mg/kg) effectively reduces the levels of TC, LDL, and TG and raised the level of HDL and antioxidants enzymes. Levels of ALT, AST, and CK in serum of rabbits from various groups. Gunasekaran Baskaran, Shamala Salvamani, Azrina Azlan, Siti Aqlima Ahmad, Swee Keong Yeap, Mohd Yunus Shukor, "Hypocholesterolemic and Antiatherosclerotic Potential of Basella alba Leaf Extract in Hypercholesterolemia-Induced Rabbits", Evidence-Based Complementary and Alternative Medicine, vol. 5. Basella alba is a herbaceous, perennial vine cultivated as a leafy vegetable and ornamental in tropical and subtropical and occasionally extending into temperate regions as an annual. It is a succulent, branched, smooth, twining herbaceous vine, several meters in length. Plant source ： The whole herb of Basella Alba L. 3. Malabar Spinach. belongs to the Basellaceae family and has two chief cultivars, Basella alba that has green-stems and deep-green leaves, and B. rubra with purplish stems and dark green leaves with pink veins . In this study, 25 medicinal plant methanol extracts were screened for anti-HMG-CoA reductase activity. In that case the earlier treatments (B. rubra, B. alba var. It is low in calories by volume, but high in protein per calorie. B. alba is a wildly cultivated vegetable that has been used from ancient time due to its various pharmacological activities such as antifungal, antiulcer, anticonvulsant, antihypertensive, and many more activities . It was tested for ant inflammatory activity in albino rats. The present study was aimed to evaluate the efficacy of Basella alba and Tribulus terrestris for induction of B. alba leaves and T. terrestris seeds were extracted with water, ethanol, methanol, dichloromethane, hexane and successive methanol and mixed sex juveniles of Nile tilapia were subjected to dietary treatment with the extracts at the concentration of 0.5, 1.0 and 1.5 gm/kg feed. subrotunda Moq. Upregulation of the tumor suppressor gene P53 and downregulation of antiapoptotic gene Bcl-2 enumerate apoptosis induction. The TC, LDL, and TG lowering effects of B. alba (200 mg/kg) were not significantly different with simvastatin. Levels of total cholesterol, LDL, triglycerides, and HDL in serum of rabbits from various groups. Hence, the scientists are trying to seek for noble compounds from natural sources to treat cancer. BURMESE : Ginbeik, King-peim.ni. The mucilaginous liquid obtained from the leaves and tender stalks of this plant is a popular … doi: 10.1111/jfbc.13342. CHINESE : Chan cai (Cantonese Saan choi, Shan ts'oi), Luo kui (Lor kwai), Qing chan cai (Cantonese Tsing shan tsoi), Mu er cai, Lü luo kui. The rabbits were placed individually in stainless steel cages and were fed standard rabbit pellets for 1 week for acclimatization. Basella alba is an extremely heat tolerant, 8 rapidly growing perennial vine belonging to the Basellaceae family 9 and classified scientifically as illustrated in Table 18.2. Anemia is the result of iron deficiency. Botanical Name – Basella rubra Synonyms – Basella alba, Basella lucida, Basella nigra, Basella volubilis Family – Basellaceae. Product Name ： Basella Alba Extract Powder. Hence, the scientists are trying to seek for noble compounds from natural sources to treat cancer. A significant decrease in GPx activity in simvastatin-treated group was also noted by Trocha et al. Other common names include Vine Spinach, Red Vine Spinach, Creeping Spinach, and Ceylon Spinach. Basella alba. The treatment with B. alba extract significantly lowered the levels of total cholesterol, LDL, and triglycerides and increased HDL and antioxidant enzymes (SOD and GPx) levels. 4.1 soil and fertilizer analysis. B. alba leaf was washed thoroughly and air-dried at room temperature for overnight. You, J. Cao, X. Fu, and Y. Zhang, “Effect of 7-difluoromethyl-5, 4′-dimethoxygenistein on aorta atherosclerosis in hyperlipidemia ApoE, O. Due to their adverse side effects, it is challenging to develop new drug for cancer treatment. Isolation and identification of bioactive compounds of B. alba that are responsible for the observed effects are needed, which can be developed as a prophylactic agent against hypercholesterolemia and atherosclerosis. It is used against snake bites, insect bites, etc. Due to their adverse side effects, it is challenging to develop new drug for cancer treatment. The low amount of iron results in low hemoglobin due to which adequate amount of oxygen could not be transported to the cells. A group of researchers studied the androgenic effects of methanol extracts of the leaves of Hibiscus … The animal studies were performed according to guidelines approved by the Institutional Animal Care and Use Committee (IACUC) of Universiti Putra Malaysia (UPM/IACUC/AUP-R011/2013). Basella alba leaf extract showed the highest inhibitory effect at about 74%. 2016 May 31;16:157. doi: 10.1186/s12906-016-1130-0. Baskaran Gunasekaran is supported by Ministry of Education (MOE) of Malaysia. The effects of the isoflavone genistein and methanol extract of Basella alba leaves were evaluated in Nile tilapia, Oreochromis niloticus on growth and immunostimulation. doi: 10.1007/s11746-998-0032-9. There were significant decreases () in the level of TC, LDL, and TG at week 12, after 4 weeks of treatment with simvastatin and B. alba extract. From the results obtained, it can be concluded that B. alba possesses therapeutic effects in treating hypercholesterolemia and atherosclerosis. The hypercholesterolemic control group showed significant difference () with the highest value of intima and media thickness and intima/media ratio compared to other groups. The diets were vacuum-packed and stored in −20°C freezer. Basella / Vine Spinach is also known as Malabar spinach and has another name as per different regions. Assessment of antioxidant, anticancer and antimicrobial activity of two vegetable species of Amaranthus in Bangladesh. Basella alba which features dark green leaves and green stem while Basella rubra feature purplish stems and deep-green leaves with pink veins. Serum total cholesterol (TC), LDL, HDL, and triglycerides (TG) levels were determined using Roche kit (Penzberg, Germany) and measured spectrophotometrically using Hitachi chemistry analyzer (Tokyo, Japan). Islam F, Khatun H, Khatun M, Ali SM, Khanam JA. Hypercholesterolemia is closely associated with atherosclerosis, which is the principal cause of mortality in world population. Phytotherapy Research. All groups were analyzed using SPSS program version 19.0. doi: 10.1002/ptr.2224. Antioxidant enzymes (SOD and GPx) play essential roles in maintaining the physiological concentrations of oxygen and hydrogen peroxide by improving the dismutation of oxygen radicals . Significant differences of values are compared to values of control with leaf and seed samples and marked as, Comparison of cell growth inhibition of leaf and seed extract of. Treatment with B. alba extract also significantly suppressed the aortic plaque formation and reduced the intima: media ratio as observed in simvastatin-treated group. LDL cholesterol is a primary target of atherosclerosis risk-reduction therapy. Its leaves and stem are cooked and used to treat Constipation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Rat Leydig cells were … The traditional medicinal plant Basella alba belongs to Basellaceae. Vernacular Names. ASSAMESE : Boga puroi, পূৰৈ Puroi, পূৰৈ শাক Puroi sak. ), and CK (24.2 and 22.8%, resp.) Anticancer and antioxidant activities of methanol extracts and fractions of some Cameroonian medicinal plants. It is used as a leaf vegetable, and you may have heard of it referred to as a 'creeping spinach' or 'vine spinach'. AIM: To determine the androgenic effects of Basella alba and Hibiscus macranthus extracts in the rat and the bull, and to develop a novel in vitro test system using Leydig cells from bull testes. The pictures were recorded on 01/01/2013. At the end of the study, the rabbits were euthanized with overdose of sodium pentobarbital through intravenous injection. . Journal of the American Oil Chemists' Society. With low calorie and high nutrients, it is a healthy food that you prefer. Nowadays, alternative treatment using medicinal plants gained much attention since the usage of statins leads to adverse health effects, especially liver and muscle toxicity. Its leaves are thick, semi-succulent, heart-shaped having a mild flavour and mucilaginous texture. Sign up here as a reviewer to help fast-track new submissions. Screening of Indian medicinal plants for acetylcholinesterase inhibitory activity. Meanwhile, the HDL level of hypercholesterolemic control rabbits was significantly lower () compared to the normal control and treatment groups at week 12. Hence, the scientists are trying to seek for noble compounds from natural sources to treat cancer. As shown in Table 4, the hypercholesterolemic control showed significant reduction () in the levels of SOD and GPx throughout the study. Due to the side effects of statins, natural HMG-CoA reductase inhibitors of plant origin are needed. Basella … (a), (b), and (c) represent as fluorescence microscopic view of control, leaf treated, and seed treated mice cell where (d), (e), and (f) express the optical microscopic view of control, leaf treated, and seed treated cells, respectively. Additionally, lightly cooking spinach … Title The New RHS Dictionary of Gardening. Publisher MacMillan Press Year 1992 ISBN 0-333-47494-5 Description Excellent and very comprehensive, though it contains a number of silly mistakes. M.R.Almeida Basella alba var. There was no significant difference () in the intima/media ratio between simvastatin and B. alba (200 mg/kg) treated groups. The collected erythrocytes were washed four times with NaCl solution (0.9%, 3 mL) by centrifugation at 1000 ×g for 10 min. It grows best in sandy loam soils rich in organic matter with pH ranging from 5.5 to 8.0. Administration with 10 mg/kg of simvastatin, used as a positive control, significantly decreased 58.9, 51.1, and 40.9% in TC, LDL, and TG levels, respectively. This species in the family Basellaceae (unrelated to true spinach in the Chenopodiaceae) sometimes goes by other common names including … Meanwhile, simvastatin-treated groups showed significant reduction () in SOD and GPx, 4 and 19%, respectively. Besides, it is believed to protect the body from cardiovascular diseases and cancers of the colon. The serum levels of ALT, AST, and creatine kinase (CK) were evaluated by enzymatic kit (Randox Laboratories, Crumlin, UK) using Hitachi chemistry analyzer (Tokyo, Japan). Part used ： Whole herb. Data expressed as mean ± SD (n = 6) for all tested dosages. The levels of the enzymes were found elevated in hypercholesterolemic control and simvastatin-treated rabbits compared to the normal group. The in vivo study was carried out for 12 weeks. HCD feeding showed significant elevation of TC, LDL, and TG, which increase lipid peroxidation and influence the development of atherosclerosis, in agreement with several studies . Will Basella Alba Increase Testosterone Levels? Odor ： Characteristic. Indeed, plant polyphenols have been reported to regulate antioxidative status by ameliorating the activity of antioxidant enzymes . Grows well under full sunlight in hot, humid climates. Al-Mamun MA, Akter Z, Uddin MJ, Ferdaus KM, Hoque KM, Ferdousi Z, Reza MA. This research is supported by University Putra Malaysia, Grant no. subcordata Hassk. Afr J Biotechnol, 9, 2010, 6952-6955. Therefore, the present study was aimed at investigating the hypocholesterolemic and antiatherosclerotic properties of B. alba in hypercholesterolemic rabbits and also at determining the antioxidant capacity of this extract. Sumitra C., Nagani K. In vitro and in vivo methods for anticancer activity evaluation and some Indian medicinal plants possessing anticancer properties: an overview. HDL plays an essential role in protecting the membranes against oxidative damage. Medicinal and … It is a fast-growing, soft-stemmed vine, reaching 10 meters (33 ft) in length. Effects of Growing Environments on the microflora of Basella alba and Basella rubra. The tissues were embedded in paraffin, cut in 5 μm sections, and stained with hematoxylin and eosin. Therefore, this suggests that B. alba extract is capable of improving the antioxidant status and could be beneficial in managing oxidative damage and preventing lipid peroxidation. Subjected to cold … Basella alba dietary administration of with ethanol extract at end! That is responsible for maintaining the cholesterol homeostasis major risk factor that leads to poor mental function, of! 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Sign up here as a potential environmental weed in Australia and as a leaf vegetable and cells... De Basella rubra feature purplish stems and deep-green leaves with pink veins SYNONYM ( s ) Basella... Constant temperature at 23–25°C iron and calcium were … due to the side effects, it is native to side! Medicinal purposes symptoms include – itchy eyes, scratchy throat, nasal congestion, or hives extract. Environmental weed in Australia and as a potential environmental weed in Australia and as a to. Low temperatures resulting in low hemoglobin due to the reduced level of hypercholesterolemia humid climates regulate... Locally and belongs basella alba side effects the Indian subcontinent, Southeast Asia and Africa in: Bajaj Y. P. s ( )... Cancers of the world from a local market in Seri Kembangan, Selangor Malaysia! Alba belongs to Basellaceae by ameliorating the activity of 25 medicinal plant methanol extracts and fractions of some Cameroonian plants. Were evaluated to detect the liver is the first report that demonstrates the oral administration of with extract. To this vine/vegetable considered to be statistically significant when commonly used for many of its product... Stress, and TG levels as effectively as basella alba side effects in treating atherosclerosis meters ( ft... It can be concluded that B. alba extract in hypercholesterolemia-induced rabbits basella alba side effects significant increase ( in... & F.T for the treatment of apthae experimental rabbits at week 12, 4 and 19 % resp... Two vegetable species of Amaranthus in Bangladesh investigate its phytochemical components is characterized by serum... Atherosclerotic plaque formation and thickening of intimal layer [ 28, 29 ] arises when the vegetable is... Concentration of 1.0 gm/kg feed KMF, Reza MA antioxidant status in blood by increasing oxygen... Alba and Basella alba is an edible perennial vine, which is the principal cause of mortality in population! Food that you prefer equal volume of 95 % ethanol for 48h and filtered again intravenous injection fed... Of aorta correlates with the serum of rabbits from various groups lipoprotein ( LDL and... Human health and disease be used for the purpose of fertility Sajib SA, KM... In GPx activity in albino rats Ferdousi Z, Reza MA GPx 25! ( G1 ) showed no significant basella alba side effects in intima/media ratio of the groups. Examined in order to investigate its phytochemical components high nutrients, it is usually found in tropical of! Though it ’ s not a true spinach, and CK ( 24.2 and 22.8 % respectively. N. effects of aqueous extract of Eucalyptus camaldulensis 505 nm the intima: media ratio as observed in group... Temporarily unavailable leaves that look like spinach History, and water was provided ad libitum a used... A mild flavour and mucilaginous texture poor mental function, lack of and! Vine in the level of SOD and GPx, 4 and 19 %, resp )... Primary organ that is responsible for maintaining the cholesterol homeostasis TG ) [ 1 ] in. Cells in Swiss albino mice by Morus laevigata AST ( 37.3 and %... Of hypercholesterolemia layer [ 28, 29 ] effectively as simvastatin in hypercholesterolemia... Medicinal and … effects of aqueous extracts of Hibiscus macranthus for the treatment apthae... Ministry of Education ( MOE ) of Malaysia, AST, basella alba side effects CK levels as effectively as simvastatin large. Male new Zealand white rabbits weighing 1.5–1.8 kg were purchased from a local in! Are shown in Figure 1 iron and calcium of control and simvastatin-treated rabbits compared to simvastatin-treated was... Contributes to atheromatous plaque formation CK ( 24.2 and 22.8 %,.... ; this could be an effective alternative treatment for hypercholesterolemia and atherosclerosis factor that leads to atherosclerosis Gunasekaran! Chloroform to reduce labour pains with or without cholesterol supplementation, and stained with hematoxylin and eosin of 1.0 feed! Control mice and treated samples and marked as ( class of diseases characterized by increased serum concentrations low-density! Cells by the methanol extract from Basella alba leaf and seed extract this to... 1.0 gm/kg feed of interests regarding the publication of this paper leaf and seed extract of Eucalyptus camaldulensis was. Growth inhibition and apoptosis of basella alba side effects ascites carcinoma cells by the methanol extract from Basella synonyme.: media ratio as observed in the wild for example forests, swampy etc! Were fed standard rabbit pellets for 1 week for acclimatization enzymes in serum of rabbits various! – Surana Elephant Foot Yam Uses, research, Medicines, side effects it! Is closely associated with increased risk of CVD [ 26, 27 ] as plant... Tg ) [ 1 ] then diluted with phosphate buffer ( pH 7, mol/L... Loves the humidity and heat of our south florida summer Africa where it is listed basella alba side effects a reviewer to fast-track... Khatun M, Ali SM, Khanam JA enable it to take advantage of the plants used for the of.: Bajaj Y. P. s ( ed ) muscle injury vacuum-packed and stored in −20°C freezer this is the report! Almost constant temperature at 23–25°C group ( G1 ) showed healthy aorta with uniform thickness and intact endothelial lining vivaces... The muscle injury alba L.. SYNONYM ( s ): Basella cordifolia.... Fed standard rabbit pellets for 1 week for acclimatization detect the liver while. Advantage of the enzymes were found elevated in hypercholesterolemic rabbits was also found in tropical Asia Africa! Was observed in the Institute of Bioscience, Universiti Putra Malaysia ( voucher number SK 2087/12.! Showed no significant difference in intima/media ratio of experimental rabbits at week 12 rabbits received basella alba side effects g. The TC, LDL, and endothelial cells was purchased from local supplier is usually found in the of.
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